Akdas E, Ilter N, Ogut B, Erdem O. Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report. The patients/participants provided their written informed consent to participate in this study. It said blood spots under the skin might also be present, either as spots or dots or on larger areas. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. JAAD Int. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. Europe PMC is an archive of life sciences journal literature. In addition to COVID-19 vaccination, she was currently taking medications (i.e., levetiracetam and thyroxin) for glioblastoma, and the two drugs had been prescribed for approximately nine months. Adverse cutaneous reactions following COVID-19 vaccines have increased, highlighting not only how SARS-CoV-2 infection but also COVID-19 vaccines may induce adverse cutaneous manifestations. PMC Cutaneous Complications of mRNA and AZD1222 COVID-19 Vaccines: A Worldwide Review. HHS Vulnerability Disclosure, Help Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. (2020) 33:e13878. Cleveland Clinic is a non-profit academic medical center. 2021;185(2):e34. Diagnoses: Rationale: Oueijan RI, Hill OR, Ahiawodzi PD, Fasinu PS, Thompson DK. Accessibility Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. N Engl J Med 2020; 383: 2603-2615. HHS Vulnerability Disclosure, Help Pityriasis Rosea-like eruptions following COVID-19 mRNA-1273 vaccination: A case report and literature review. Keywords: adverse effect, coronavirus, cutaneous eruptions, immunization, pityriasis rosea, SARS-CoV-2, vaccine, case report, Citation: Leerunyakul K, Pakornphadungsit K and Suchonwanit P (2021) Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. doi: 10.1111/jdv.17342. "Like a lot of things in dermatology, unfortunately, we're not always sure what causes these rashes," says Lam. Various mild and benign cutaneous manifestations of the different forms of the COVID-19 vaccine have been documented. Pityriasis rosea usually resolves on its own without treatment in most cases, King says, but topical corticosteroids can be used for itchy control if necessary, which is what I used. Would you like email updates of new search results? Sprinkle bath water with an oatmeal-based bath product (Aveeno). Bin Rubaian NF, Almuhaidib SR, Aljarri SA, Alamri AS. 7 Articles, This article is part of the Research Topic, Creative Commons Attribution License (CC BY), Division of Dermatology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. An official website of the United States government. Factors affecting the severity of central centrifugal cicatricial alopecia. 2022 Nov 1;43(6):555-558. doi: 10.2500/aap.2022.43.220058. 8 In some cases, antibodies against HHV6/7 as well as viral DNA in plasma and PBMCs were detected. Bookshelf Herald patch in the right hypochondrium followed by typical oval-shaped secondary plaques, Pityriasis rosea lesions on the upper extremities, MeSH Fortunately, PR-like eruption is responsive to topical corticosteroids without any systemic adverse effects. Additional evidence that pityriasis rosea is associated with reactivation of human herpesvirus-6 and -7. Epub 2022 Jun 21. National Library of Medicine Bathe or shower in lukewarm water. At home, she underwent systemic treatment with antihistamines and topical medication with dermatocorticosteroids. Most people with the rash are 10 to 35 years of age. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: a registry-based study of 414 cases. Dermatol Ther. The papulovesicular and pityriasis rosea . All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work. (2021) 60:11501. sharing sensitive information, make sure youre on a federal If you have pityriasis rosea, the rash with go away without treatment. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. In conclusion, we have described the first case of PR-like eruption following ChAdOx1 nCoV-19 (Oxford/AstraZeneca) vaccination. The transformation will take your breath away. Med Clin (Barc). Disseminated erythematous-papulosquamous lesions, with right laterocervical herald patch (clinical aspect on admission). Epub 2022 Feb 9. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. All rights reserved. Hardin J. Pityriasis Rosea. You also wont have permanent scarring or other damage to your skin. Following the national COVID-19 vaccination guidelines, she received a shot of ChAdOx1 nCoV-19 (AZD1222) vaccine before the therapy. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 Vaccine J Eur Acad Dermatol Venereol. Dermoscopy showed dotted and linear vessels forming a network on a yellowish background, with some whitish peripheral scales (Figure 3A). Accessibility The available COVID-19 vaccines entail different levels of risk for skin reactions. sharing sensitive information, make sure youre on a federal Epub 2022 Feb 9. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Federal government websites often end in .gov or .mil. Pityriasis rosea: An update on etiopathogenesis and management of difficult aspects. 2022 Sep;21(9):3692-3703. doi: 10.1111/jocd.15209. Had I started new medication? Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Your skin may develop discolored patches (lesions) that look like scales or dry, crinkly paper. -, Drago F, Ciccarese G, Javor S, Parodi A. Vaccineinduced pityriasis rosea and pityriasis rosealike eruptions: a review of the literature. 2022 Mar 9;35(3):342-343. doi: 10.1080/08998280.2022.2044742. J Med Virol 2021; 93: 1850-1851. -, Recalcati S. Cutaneous manifestations in COVID-19: a first perspective. (2017) 9:7399. doi: 10.4081/dr.2017.7399, 17. doi: 10.1111/bjd.20143. In: Jameson J, Fauci AS, Kasper DL, et al., eds. There isnt a cure, but it isnt contagious. Bethesda, MD 20894, Web Policies doi: 10.1159/000517971. Epub 2020 Nov 20. In: Papadakis MA, McPhee SJ, Bernstein J., eds. Bethesda, MD 20894, Web Policies Influenza viruses and vaccines have triggered pityriasis rosea in some cases.". The site is secure. Though pityriasis rosea is a common skin rash, it can still make you feel self-conscious, and it can be unpleasant if it itches. Bethesda, MD 20894, Web Policies Recurrent and persistent pityriasis rosea: an atypical case presentation. These skin conditions can include, among other things, hives, measles-like rashes and a full body rash similar to pityriasis rosea. doi: 10.1111/jdv.17342. Pityriasis rosea is a rash that usually appears on the torso, upper arms, thighs or neck. JAAD Int. The patient presented to the Department of Dermatology for a 3 week duration of an extremely pruritic erythematous-squamous lesion, initially on the trunk and upper limbs, with extension to the lower limbs in the last week and the lesion respected the cephalic extremity, palms, and soles. -. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. National Library of Medicine Urbina F, Das A, Sudy E. Clinical variants of pityriasis rosea. eCollection 2022. doi: 10.7759/cureus.22414. I video-chatted with my dermatologist who asked a few questions: Did I have body aches or flu-like symptoms? Foods that have anti-inflammatory properties include: Foods that may increase inflammation include: There isnt any way to prevent pityriasis rosea. The authors of one 2014 case report of a 71-year-old man who suffered from pityriasis rosea one month after receiving an influenza vaccine concluded that "altered immunity" could result in reactivation of HHV-6 and/or HHV-7 which may have triggered an atypical presentation of PR. Rashes should be considered a "key diagnostic sign" of Covid-19, according to a study, which found 8% of people who test positive for the virus have some form of rash. Med. And the itch usually only lasts for a few days mine finally let up around day seven but the rash can leave behind dark marks that eventually resolve on their own, Lam says. The most commonly reported features . We present a case of a pityriasis rosea-like rash occurring after Pfizer COVID-19 vaccination and review cases of pityriasis rosea (PR)/PR-like eruption (PR-LE) after mRNA COVID-19 vaccine published in the medical literature. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. Bookshelf Unfortunately, due to her deteriorating neurologic status, her associated symptoms were not evaluated properly. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. and transmitted securely. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Chanprapaph K, Pomsoong C, Tankunakorn J, Eden C, Suchonwanit P, Rutnin S. Comparative analyses of clinical features, histopathology, and CD123 immunohistochemistry of oral lupus erythematosus, lichen planus, and other lichenoid lesions. This site needs JavaScript to work properly. Accessibility A spectrum of cutaneous reactions to SARs-CoV-2 (COVID-19) vaccines have been reported in the literature. The rash itself usually doesnt blister or bleed, but in many cases, the skin may peel. Many Americans become infected with them at an early age. Epub 2022 Jan 31. Epub 2022 Feb 9. What started as a single, quarter-inch raised welt on my left rib cage eventually morphed into two, then four. Few brownish patches also appeared, suggestive of post-inflammatory hyperpigmentation. Leerunyakul K, Pakornphadungsit K, Suchonwanit P. Front Med (Lausanne). Treatment with topical 0.1% triamcinolone acetonide twice per day showed partial response after seven days. NCI CPTC Antibody Characterization Program. The study said the appearance was similar to pityriasis rosea, a common skin condition. 2021 Aug;185(2):e34. The appearance of pityriasis rosea following the first injection of the AstraZeneca vector vaccine suggests a causal connection. J Am Acad Dermatol. National Library of Medicine Clipboard, Search History, and several other advanced features are temporarily unavailable. One week before the rash, respiratory tract infection symptomatology was observed by the patient. doi: 10.1007/s10103-019-02783-8, 16. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. Even though it is benign, it can cause substantial. doi: 10.1111/bjd.20143. sharing sensitive information, make sure youre on a federal official website and that any information you provide is encrypted Moreover, almost all lesions faded with associated post-inflammatory hyperpigmentation (Figure 2B). The https:// ensures that you are connecting to the Published by Wolters Kluwer Health, Inc. If I dont have pityriasis rosea, what other skin condition might I have? Pityriasis rosea-like eruption presenting as multiple discrete erythematous oval patches and plaques on the back (A) lower abdomen, and bilateral upper thighs (B); lesions distributed along cleavage lines without prominent scales (C). Epub 2022 Jan 5. It's also what's known as a self-limiting rash, Hartman says, in that it can resolve itself on its own without treatment in about six to eight weeks. Would you like email updates of new search results? 2020 Sep 25;155(6):273. doi: 10.1016/j.medcli.2020.05.024. Some treatments can alleviate related symptoms, including itching. Parakeratosis with minimal acanthosis, MeSH J Eur Acad Dermatol Venereol. It is likely that a new viral trigger of pityriasis rosea is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). See this image and copyright information in PMC. -, Carballido Vzquez AM, Morgado B. Pityriasis rosea-like eruption after PfizerBioNTech COVID-19 vaccination. Temiz SA, Abdelmaksoud A, Dursun R, Durmaz K, Sadoughifar R, Hasan A. J Cosmet Dermatol. 2022 May;11(2):222-225. doi: 10.7774/cevr.2022.11.2.222. Lessons: Some patients may have a cold before the rash. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. However, if you experience any symptoms, therapy can provide relief. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. Pityriasis rosea (PR)-like eruption is a cutaneous complication associated with several medications and vaccinations. I tell my patient to use a gentle non-soap cleanser." Dermatologic side effects of COVID-19 vaccines range from morbilliform rash and pernio to pityriasis rosea and erythema multiforme. Unable to load your collection due to an error, Unable to load your delegates due to an error. ", Though there's no single-known cause, King says, "pityriasis rosea is associated with reactivation of herpesviruses 6 and 7 [HHV-6 and HHV-7, respectively], which cause the primary rash, roseola, in infants. Federal government websites often end in .gov or .mil. Dermatol Online J. Epub 2021 May 29. PMC -, Neoh CY, Tan AW, Mohamed K, et al. official website and that any information you provide is encrypted Dermatology. Shabazz DR. Pityriasis Rosea. Cutaneous Reactions Following COVID-19 Vaccination: A Review of the Current Literature. -, Carballido Vzquez A.M., Morgado B. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. Allergy Asthma Proc. Birlutiu V, Dobritoiu ES, Lupu CD, Herteliu C, Birlutiu RM, Dragomirescu D, Vorovenci A. FOIA The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Ehsani AH, Nasimi M, Bigdelo Z. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection. Zendaya Shows Off Her Short Sunshine Curls. . Epub 2021 Jul 21. Bookshelf However, if it does, the symptoms may last for a longer period. Histopathologic features: (B) microscopic image at a low power field showing psoriasiform epidermal hyperplasia, perivascular infiltration, and interface dermatitis (hematoxylin-eosin; scale bar represents 100 m); (C) microscopic image at a high power field showing focal spongiotic dermatitis, interface dermatitis, and perivascular infiltration of lymphocytes and eosinophils (hematoxylin-eosin; scale bar represents 40 m). ", The 29 Best Valentines Day Gifts for the Men in Your Life. Copyright 2021 the Author(s). Please enable it to take advantage of the complete set of features! They indicate that eight types of rash could be signs of Covid-19, including red toes and fingers, chest eczema and pityriasis rosea (scroll down for the full list). -, Johansen M, Chisolm SS, Aspey LD, Brahmbhatt M. Pityriasis rosea in otherwise asymptomatic confirmed COVID-19-positive patients: a report of 2 cases. MeSH J Eur Acad Dermatol Venereol. Br J Dermatol. The herald patch is the telltale sign that your rash could be PR, but there are other common (though not universal) symptoms as well. eCollection 2022. These findings were consistent with a diagnosis of PR-like eruption. government site. The evolution was unfavorable, with the spread of the lesions and the accentuation of the pruritus. 2021;35(8):e489e491. sharing sensitive information, make sure youre on a federal Numerous scattered erythematous plaques with fine scale oriented along skin cleavage, Herald patch of pityriasis rosea. Women and young people are most likely to have these reactions. Numerous scattered erythematous plaques with fine scale oriented along skin cleavage lines, most appreciable on the upper portion of the chest. In: Kelly A, Taylor SC, Lim HW, et al., eds. In a registry-based study, PR-like eruption was observed in only 12% of patients (14). The .gov means its official. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. -. These types cannot cause cold sores or genital herpes. Epub 2022 May 31. A 3-cm oval plaque with peripheral scale, larger than the other lesions, was present on the inferior portion of the right breast. KL and KP collated resources. Bookshelf Got an extremely itchy rash that came seemingly out of nowhere? However, adverse effects to COVID-19 vaccines, particularly cutaneous reactions, have been reported. Br J Dermatol. Before Our reported case adds to the other findings regarding the association of PR with SARS-CoV-2 infection, in the context of the pandemic, suggesting the need to test patients with PR skin lesions for SARS-CoV-2 infection. This patch is the herald or mother patch. Viruses, Variants, and Vaccines: How COVID-19 Has Changed the Way We Look at Skin. The etiopathogenesis of PR is still unknown, but is frequently associated with episodes of upper respiratory tract infections. Please enable it to take advantage of the complete set of features! Careers. The Covid Symptom Study. Kroumpouzos G, Paroikaki ME, Yumeen S, Bhargava S, Mylonakis E. Microorganisms. 2021;185(2):e34. Polack FP, Thomas SJ, Kitchin N, et al. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. J Am Acad Dermatol. Bookshelf JAAD Case Rep. 2021;7:9394. Unauthorized use of these marks is strictly prohibited. . Pityriasis rosea (PR) is an acute papulosquamous cutaneous disorder that classically presents with a herald patch rapidly followed by a widespread rash along skin cleavage lines. Disclaimer. (d) Patient 2: Closeup of plaques, with the hyperpigmented centre and trailing scale. Epub 2022 Jun 21. 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. Our expert physicians and surgeons provide a full range of dermatologic, reconstructive and aesthetic treatments options at Cleveland Clinic. 2022 Aug;20(8):1123-1124. doi: 10.1111/ddg.14784. Herein, we are reporting a unique. Rybak-d'Obyrn J, Placek W, Owczarczyk-Saczonek A, Derkaczew M, Joniec E, Hofman R, Stompr M. Clin Cosmet Investig Dermatol. J Am Acad Dermatol. Adya KA, Inamadar AC, Albadri W. Post Covid-19 vaccination papulovesicular pityriasis rosea-like eruption in a young male. Epub 2022 Jun 21. Before Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. | Pityriasis Rosea, COVID-19 and . Cured meats with nitrates, such as hot dogs. Epub 2022 Jan 31. Cutis. Suchonwanit P, Hector CE, Bin Saif GA, McMichael AJ. eCollection 2022 Feb. Kroumpouzos G, Paroikaki ME, Yumeen S, Bhargava S, Mylonakis E. Microorganisms. However, some people believe that eating an anti-inflammatory diet may relieve itching. In darker-skinned or Black people, the patches may be more raised (papular), and the centers of the patches may look like the tissue is dying (necrotic). -, Polack FP, Thomas SJ, Kitchin N et al. doi: 10.1111/jdv.12942, 13. A 3-cm oval plaque with peripheral scale, larger, MeSH Of the 30 cases found, none experienced severe adverse effects and the rash resolved in an average of 5.6 weeks. "There's some emerging data where there are certain skin rashes that seem to be more associated with the COVID vaccine, and pityriasis rosea is one them. Careers. 2020 Jul;33(4):e13730. Epub 2021 Apr 7. Epub 2021 May 29. An official website of the United States government. J Med Virol. An official website of the United States government. 8600 Rockville Pike See this image and copyright information in PMC. 2021 Oct;20(10):3080-3084. doi: 10.1111/jocd.14372. HHS Vulnerability Disclosure, Help doi: 10.1111/dth.13650, 7. Some people who have had cosmetic fillers used to remove . HHS Vulnerability Disclosure, Help No use, distribution or reproduction is permitted which does not comply with these terms. (a) Patient 1: Thin, Histopathological findings of pityriasis rosealike, Histopathological findings of pityriasis rosealike eruption in patient 1. Generalized Papulovesicular Eruption as a Side Effect of the Pfizer-BioNTech COVID-19 Vaccine. Pityriasis rosea is a common condition that causes discolored patches on your skin. However, in cases of atypical PR, it may present with erythema multiforme-like lesions and purpura (5). National Library of Medicine They develop in a pattern that resembles sagging Christmas tree branches. Published by Elsevier Inc. Pityriasis rosea. Epub 2021 Nov 2. Clipboard, Search History, and several other advanced features are temporarily unavailable. (No.) Involvement of the oral mucosa has also been reported in as many as 50% of all cases (11). Pityriasis Rosea Shortly After mRNA-1273 COVID-19 Vaccination. 2022 by the American Academy of Dermatology, Inc. doi: 10.1002/jmv.26549, 9. doi: 10.1111/ijd.15700, 4. Dtsch Arztebl Int. However, if you scratch your patches, you may break your skin, leading to an infection that can cause pain. Received: 03 August 2021; Accepted: 17 August 2021; Published: 07 September 2021. Treatment may include various topical and oral drugs. Global prevalence and clinical manifestations of cutaneous adverse reactions following COVID-19 vaccination: A systematic review and meta-analysis. Your healthcare provider can typically diagnose pityriasis rosea after a physical exam. The .gov means its official. The .gov means its official. Pityriasis rosea commonly affects the skin on your trunk, arms or legs. Pityriasis rosea Gibert is an erythematous-papulosquamous dermatosis that frequently occurs in young adults.
Advantage Of Standard Deviation Over Mean Deviation, Articles P