Jurcu, R., & Jurcu, I. Stickel F, Seitz HK. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. In a small study with 30 subjects, lower back pain from exercise was reduced with an ointment containing comfrey. 1 Since at least the 4 th century, people have used comfrey medicinally. Comfrey contains chemicals that cause serious liver damage when taken by mouth. Comfrey [Online article]. These have a lower risk of serious side effects like liver damage. You and your healthcare provider should weigh the pros and cons and use it only under their supervision. Penetration of lycopsamine from a comfrey ointment through human epidermis. 12 drops black pepper (Piper nigrum) essential oil Br J Sports Med. Call your doctor for medical advice about side effects. However, it did not affect markers of inflammation or cartilage breakdown over 12 weeks of treatment. Skin patch test before use, especially if you have sensitive skin, and never use on a deep wound. Comfrey is generally considered unsafe, with numerous toxicological effects in animals and humans. Mazzocchi, A. and Montanaro, F. Observational study of the use of Symphytum 5CH in the management of pain and swelling after dental implant surgery. J Pharmacopuncture 2021;24(4):196-205. Most comfrey oils keep for around 2 years after production. Arzneimittelforschung. Comfrey root: from tradition to modern clinical trials, Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo-controlled, multicentre trial, Topical herbal therapies for treating osteoarthritis, Effect of a blend of comfrey root extract (Symphytum officinale L.) and tannic acid creams in the treatment of osteoarthritis of the knee: randomized, placebo-controlled, double-blind, multiclinical trials, Treatment with 4Jointz reduces knee pain over 12 weeks of treatment in patients with clinical knee osteoarthritis: a randomised controlled trial. (2004). Comfrey has also been used for the following conditions: There is currently not enough evidence to recommend comfrey cream for any of these uses. It is called knitbone or boneset, referring to the bone-like growth of its roots. It also came as a reference to the belief that comfrey can mend broken bones. Although not all side effects are known, comfrey is thought to be possibly safe when applied to unbroken skin for less than 10 days. 2005 - 2023 WebMD LLC. After the tincture is made, then you can whip up the fabulous joint and muscle cream! Be sure to choose organic carrier oils and essential oils when possible. Can comfrey be used for cracked nipples during breastfeeding? 2007;57(11):712-716. Available at: https://www.cfsan.fda.gov/~dms/dspltr06.html. You should never ingest comfrey by mouth. Copyright Holland & Barrett Retail Limited, 2022. Therapeutic use of comfrey is limited because of its toxicity. (2018). Smith, D. B., & Jacobson, B. H. (2011). One study followed 142 patients with ankle sprains. View abstract. Please read the Topical Use Safety section of this article (above) before using. Comfrey may also be used for purposes not listed in this product guide. Stewart MJ, Steenkamp V. Pyrrolizidine poisoning: a neglected area in human toxicology. Ask a doctor, pharmacist, or other healthcare provider if it is safe for you to use this product if you have: Comfrey is considered likely unsafe to use during pregnancy. Amendments to the poison list. For one of these studies, the average time participants had experienced knee pain and stiffness leading up to the study was six and a half years! Comfrey is considered likely unsafe to use if you are nursing a baby. Frost R, O'meara S, Macpherson H. The external use of comfrey: a practitioner survey. Barna, M., Kucera, A., Hladikova, M., & Kucera, M. (2012). This recipe is contraindicated for small children and those with certain medical conditions. Comfrey (Symphytum officinale) is a plant with yellow or purple flowers found in Europe, Asia, and North America. With extract of Comfrey. Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin. Swiss.Med.Wkly. Natural Standard. Phytomedicine. The Herbal Academy supports trusted organizations with the use of affiliate links. View abstract. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., and Staiger, C. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study. View abstract. They help us to understand how people use the website and give us the ability to provide targeted marketing to you. 95 ($14.78/Fl Oz) FREE delivery Wed, Mar 8 on $25 of items shipped by Amazon. The chemicals contained in comfrey may cause birth defects. Comfrey cream combines ingredients like oils or water and glyceryl stearate with Symphytum officinale (comfrey) extracts. Liver injury from herbal and dietary supplements. View abstract. Many of those following the folk use of comfrey up to present-day think so. Recent studies have suggested topical benefits, but more research is needed. When harvesting comfrey or buying from a non-commercial supplier, note that there is variety within the species. https://doi.org/10.1007/s10354-007-0474-y. Make sure to always buy comfrey (Symphytum officianale) root and leaf from a trusted source. Tunon, H., Olavsdotter, C., and Bohlin, L. Evaluation of anti-inflammatory activity of some Swedish medicinal plants. Tanret, I. and Duh, D. [Pharmaceutical sheet. 1 It's found in Europe, Asia, and North America. Arzneimittelforschung, 62(06), 285-289. https://doi.org/10.1007/s10354-007-0474-y, Giannetti, B. M., Staiger, C., Bulitta, M., & Predel, H. G. (2010). Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid. The study involved 43 patients with knee osteoarthritis and a six-week treatment period. We currently have no information for COMFREY overview. Double boiler Topically applied comfrey oil is associated with a wide range of health benefits and can help with certainissues including: Comfrey oil is good at helping with superficial cuts, scratches, and scrapes. These side effects may be common or severe. The Pharmaceutical Journal, PJ, December 2007. Penetration of lycopsamine from a comfrey ointment through human epidermis. Avoid using comfrey extracts on broken skin or open wounds. 1. Wound-healing effects of a symphytum herb extract cream (. The Comfrey Ointment that I have been using is to be used only for sprains and bruises. Verywell Health's content is for informational and educational purposes only. Its ready when the mixture has solidified somewhat and has a cloudy, creamy, and slightly runny consistency. randomized, placebo-controlled, double-blind, multi-clinical trial. hollandandbarrett.com is a trading name of Holland & Barrett Retail Limited,. (2001). Huxtable RJ, Awang DV. J Pharm.Belg. Stop using comfrey and call your healthcare provider at once if you have: liver problems-- nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). Whether youre familiar with it or not, this unusual herbal remedy is definitely worth knowing more about. If you're considering using the cream, consult your healthcare provider first. Book your free, one-to-one online consultation with one of our qualified advisors. Proliferative and antioxidant activity of Symphytum officinale root extract. The ointment has a very mild herbal fragrance and is soothing on application. Safety Alerts & Advisories: FDA Advises Dietary Supplement Manufacturers to Remove Comfrey Products From the Market. Drug-induced liver injury. View abstract. Jedlinszki N, Balzs B, Csnyi E, Csupor D. Penetration of lycopsamine from a comfrey ointment through human epidermis. Comfrey can kill. This article discusses the uses and benefits of comfrey cream. This perennial can grow up to 4-feet tall. Book your free, one-to-one online consultation with one of our qualified advisors. Sowa I, Paduch R, Strzemski M, et al. (2018). The leaves and stems of comfrey contain pyrrolizidine alkaloids that can cause toxic damage if ingested in excess (Ulbricht, 2010). Giannetti, B. M., Staiger, C., Bulitta, M., and Predel, H. G. Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind, randomised, placebo controlled, multicentre trial. 2012;(1):41-42. Retrieved from https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295, Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). This was compared to 37.8% in the placebo group. And topical capsaicin cream may help to relieve pain temporarily. Staiger, C. Comfrey root: from tradition to modern clinical trials. Documented adverse effects (the pyrrolizidine alkaloids, have substantial risk of causing fatal liver damage and can cause abortion). Choose a supplement tested by a trusted third party, such as USP, ConsumerLabs, or NSF when possible. The Comfrey Controversy: Can and Should One Use Comfrey Internally? Wien.Med Wochenschr. Toxicol Lett 2005;155:411-20. Its long, lance-shaped leaves can be up to 1 foot in length closer to the bottom of the stem and are shorter higher up the stem. Patients with hypersensitivity or allergic reactions to the plant should also avoid external use. Anotherstudy found that comfrey ointment was superior to placebo in relieving pain and stiffness in osteoarthritis. Retrieved from, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., Giannetti, B., Klingenburg, S., and Staiger, C. Efficacy and tolerance of a comfrey root extract (Extr. Efficacy and tolerance of a comfrey root extract (Extr. Here's 10 things essential oils are great for. In a multicenter, randomized, double-blind, placebo-controlled study with 142 ankle sprain participants, a comfrey root extract applied 4x/day for 8 days improved pain, swelling, and mobility without any adverse reactions (Koll et al., 2004). View abstract. (10), 707-714. https://doi.org/10.1016/j.phymed.2005.06.001. Healthy adults: massage about 1 teaspoon of cream into a local area up to 4x/day for up to 2 weeks. The herbal topical cream was prepared at two different strengths, as an additional measure of efficacy.
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