This list covers only some interactions. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. 2023 eHealthMe.com. It is best not to drink alcohol while you are on isosorbide mononitrate. Talk to your pharmacist for more details. During pregnancy, this medication should be used only when clearly needed. Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Accessed Sept. 7, 2022. (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. This content does not have an Arabic version. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: continuing ringing or buzzing or other unexplained noise in the ears, dull ache or feeling of pressure or heaviness in the legs, excess air or gas in the stomach or intestines, increased sensitivity of the eyes to sunlight, loss in sexual ability, desire, drive, or performance, pain or tenderness around the eyes and cheekbones, redness of the face, neck, arms, and occasionally, upper chest, redness, pain, swelling of the eye, eyelid, or inner lining of the eyelid, redness, swelling, or soreness of the tongue, small clicking, bubbling, or rattling sounds in the lung when listening with a stethoscope, stomach bloating, burning, cramping, or pain, terrifying dreams causing sleep disturbances, uncontrolled twisting movements of the neck, white patches in the mouth, tongue, or throat. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. In case of overdose, call the poison control helpline at 1-800-222-1222. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Isosorbide mononitrate (Monoket) can cause some serious health issues. Isosorbide tablets are also used with other medications to treat heart failure. Discuss the risks and benefits with your doctor. Upgrade to Patient Pro Medical Professional? Accessed Sept. 7, 2022. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. official website and that any information you provide is encrypted However, you should not flush this medication down the toilet. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. This information is aggregated and used to produce personalized reports that patients can reference. Patient is a UK registered trade mark. In the US - Call your doctor for medical advice about side effects. All rights reserved. Isosorbide mononitrate (Monoket) works slowly to help prevent chest pain. Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. Aspirin has an average rating of Do not try to change the times or the way that you take isosorbide in order to avoid headaches because then the medication may not work as well. In: Current Medical Diagnosis & Treatment 2022. Click here for an email preview. Isosorbide mononitrate (Monoket) is available as both a immediate-release (IR, short-acting) and extended-release (ER, long-acting) tablet. This site complies with the HONcode standard for trustworthy health information: verify here. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088). Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. Available for Android and iOS devices. Keep all medicines out of the reach and sight of children. May also be prescribed off label for Esophageal Spasm. Accessibility If you have recently had a head injury or a heart attack. This medication may interfere with certain laboratory tests (including cholesterol levels), possibly causing false test results. Isosorbide (C6H10O4), also called D-Isosorbide dinitrate, is a bio-product sourced from starch. What are the interactions of Isosorbide Mononitrate ? Ask your pharmacist for a list of the ingredients. This should pass after a few days. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. It can cause your blood pressure to become dangerously low. Advertising revenue supports our not-for-profit mission. Browse Drugs and Medicines. What special dietary instructions should I follow? Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). http://www.upandaway.org. The dose is according to the body weight and severity of the condition. Do not drink alcohol while taking View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions. 19 are major, 174 are moderate, and 2 are minor. Thirty percent of the patients never experienced headache from the given dosages. Egton Medical Information Systems Limited. This is because the tablets/capsules are specially made to release the medicine they contain in a controlled way. And as many as 25% of people also take medicines ordered for them by their health care providers, also called prescription medicines. You can take your doses either before or after meals. Isosorbide dinitrate dose 30-120 mg daily in divided doses. Isosorbide mononitrate has an average rating of 46 ratings on Drugs.com. Isosorbide mononitrate is used to prevent chest pain (angina) in patients with a certain heart condition (coronary artery disease). Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks ( chest pain ). Generic alternatives may be available. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. Laboratory and/or medical tests (such as blood pressure) should be performed periodically to monitor your progress or check for side effects. A very serious allergic reaction to this drug is rare. If you become pregnant while taking isosorbide, call your doctor. other information we have about you. Coenzyme Q-10 Natural Medicines. Store at room temperature away from light and moisture. The .gov means its official. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. This is not a complete list of possible side effects. Do not share this medication with others. Which drugs or supplements interact with isosorbide mononitrate? Murray MT. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. The tablet usually is taken two or three times daily. Isosorbide controls chest pain but does not cure coronary artery disease. Some of these medicine interactions can be risky. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. Accessed Sept. 7, 2022. Severe postural hypotension with light-headedness and dizziness is frequently observed after the consumption of alcohol. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Herbal supplements can interact with medicines used to treat heart and blood vessel problems, such as high blood pressure and heart failure. Swallow the tablet/capsule whole - do not chew or crush it before you swallow. This content does not have an English version. It will not treat an angina attack that has already begun. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. Seek alternatives to the CYP3A4 substrate when possible. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. Take isosorbide exactly as directed. Methods: Some products have ingredients that could worsen your heart failure. It can cause your blood pressure to become dangerously low. (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. If your chest pain attacks happen more often, last longer, or become more severe at any time during your treatment, call your doctor. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. Mayo Clinic does not endorse companies or products. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. Medicines containing Isosorbide Mononitrate. 72% of reviewers reported a positive effect, while 12% reported a negative effect. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. For haemoglobin formation vit. Hawthorn. If concomitant therapy cannot be avoided, monitor clinical effects of the . Consult your doctor before breast-feeding. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Instead, the best way to dispose of your medication is through a medicine take-back program. Ask your doctor before using aspirin together with alcohol. Diabetes treatment: Can cinnamon lower blood sugar? flushing - try to cut down on coffee, tea and alcohol because they can make flushing worse. Natural Medicines. All rights reserved. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? Some conditions may become worse when the drug is suddenly stopped. National Library of Medicine If it is within 2 hours of the next dose, skip the missed dose. Disclaimer. GoodRx works to make its website accessible to all, including those with disabilities. This medicine is for you. Unless there is a specific reason you need the brand, the generic medication will be a better value. You may report side effects to the FDA at 1-800-FDA-1088. Glyceryl trinitrate (GTN) is commonly prescribed for this. It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. Meinertz T, Lehmacher W; Trapidil/ISDN Study Group. Be sure to follow your provider's instructions about when to take isosorbide mononitrate (Monoket). Before Isosorbide mononitrate helps to prevent angina chest pain from developing. Heres what you need to know about alcohol and blood pressure including how alcohol can interact with your blood pressure medications. Isosorbide mononitrate systemic 60 mg (A ID). amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. prevention of anginal chest pain associated with coronary artery disease, prevent bleeding varicose vein in the esophagus. St. John's wort. 2017; doi:10.1016/j.jacc.2016.11.078. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. As precautionary measure, it is preferable to avoid the use of isosorbide mononitrate during pregnancy. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Use this medication regularly to get the most benefit from it. Saw palmetto. Many people using this medication do not have serious side effects. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). To view a report comparing 3 (or more) medications, please sign in or create an account. https://naturalmedicines.therapeuticresearch.com. No, that's not true all the time. But only about 25% of people who take herbal supplements tell their health care providers. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, List Isosorbide Mononitrate side effects by likelihood and severity. Elantan, Imdur, Isotard, Monomax, Tardisc, Xismox. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. This survey is being conducted by the WebMD marketing sciences department. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Unable to load your collection due to an error, Unable to load your delegates due to an error. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. It is important that you follow the instructions your doctor gives to you about when to take your doses. Evening primrose. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Do not take a double dose to make up for a missed one. The https:// ensures that you are connecting to the HHS Vulnerability Disclosure, Help Review/update the It is not intended as medical advice for individual conditions or treatment. So get a ct scan brain apart from cardiology workup. This site needs JavaScript to work properly. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. Clipboard, Search History, and several other advanced features are temporarily unavailable. It is not suitable to take to treat an angina attack - you should always carry with you a short-acting nitrate, such as glyceryl trinitrate (GTN), for if you get angina pain. It is also important information to carry with you in case of emergencies. Call your doctor for medical advice about side effects.
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